With an increasing number of total knee arthroplasty and total hip arthroplasty procedures being performed in the United States, the rate of failure has also increased. In its annual report, the American Joint Replacement Registry listed infection as a leading cause of TKA and THA revisions from 2012 to 2016. Research has also shown failures due to periprosthetic joint infection are expected to increase at an annual rate of between 38,000 cases and 270,000 cases by the year 2030.